Article

Renal-predominant FOXP3-related immune dysregulation with ALPS-like lymphoproliferation: a case report

2026-08-03

Abstract excerpt

<title>Abstract</title> <p>Background FOXP3 controls regulatory T-cell development and function. Pathogenic variants in X-linked FOXP3 cause IPEX syndrome. Classic IPEX includes early enteropathy, insulin-dependent diabetes, and eczema. Some patients show non-classic disease. These forms may involve the kidney, blood, or lymph nodes. Method We report a 3-year-old boy with a kidney-predominant presentation. He h...

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Literature Corpus work: db778829-b043-51a9-82ff-73bfdacacb1e
DOI: 10.21203/rs.3.rs-10267923/v1

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