Interaction between common variants of FTO and MC4R is associated with risk of PCOS.

doi:10.1186/s12958-015-0050-z

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Article

Interaction between common variants of FTO and MC4R is associated with risk of PCOS.

Reproductive biology and endocrinology : RB&E - 2 Jun 2015

Yuan Huiqin, Zhu Guoping, Wang Fang, Wang Xiang, Guo Huihui, Shen Mo

Abstract excerpt

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common and complex endocrine-metabolic disease. One of the well-documented characteristics of PCOS is obesity or overweightness. It is possible to be genetically predisposed to becoming obese or overweight, and several potentially causative single nucleotide polymorphisms (SNPs), such as rs9939609 (A/T) in the fat mass, and obesity-associated gene (FTO) and...

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PMID: 26032905
DOI: 10.1186/s12958-015-0050-z
PMCID: PMC4455322

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