Article
Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents.
Journal of proteome research - 7 May 2010
Saric Jasmina, Li Jia V, Swann Jonathan R, Utzinger Jürg, Calvert Gail, Nicholson Jeremy K, Dirnhofer Stephan, Dallman Maggie J, Bictash Magda, Holmes Elaine
Abstract excerpt
Parasitic infections cause a myriad of responses in their mammalian hosts, on immune as well as on metabolic level. A multiplex panel of cytokines and metabolites derived from four parasite-rodent models, namely, Plasmodium berghei-mouse, Trypanosoma brucei brucei-mouse, Schistosoma mansoni-mouse, and Fasciola hepatica-rat were statistically coanalyzed. (1)H NMR spectroscopy and multivariate statistical analysis...
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