Article
Family-based analysis of MSX1 haplotypes for association with oral clefts.
Genetic epidemiology - 1 Sept 2003
Fallin M Daniele, Hetmanski Jacqueline B, Park Jiwan, Scott Alan F, Ingersoll Roxann, Fuernkranz Hans A, McIntosh Iain, Beaty Terri H
Abstract excerpt
Oral clefts, one of the most common forms of birth defects, are considered to be of complex etiology, including both genetic and environmental causes. To date, however, no particular genetic cause has been confirmed for isolated, nonsyndromic oral clefts. Previous case-control and family-based association studies reported an association between an intronic CA repeat of the MSX1 gene and risk for oral clefts. In...
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