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Article

Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing.

Science (New York, N.Y.) - 5 Oct 2007

Bäurle Isabel, Smith Lisa, Baulcombe David C, Dean Caroline

Abstract excerpt

The RRM-domain proteins FCA and FPA have previously been characterized as flowering-time regulators in Arabidopsis. We show that they are required for RNA-mediated chromatin silencing of a range of loci in the genome. At some target loci, FCA and FPA promote asymmetric DNA methylation, whereas at others they function in parallel to DNA methylation. Female gametophytic development and early embryonic development...

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Identifiers

PMID: 17916737
DOI: 10.1126/science.1146565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing.PMID 17916737Read ↗

Differential interactions of the autonomous pathway RRM proteins and chromatin regulators in the silencing of Arabidopsis targets.Semantic proximity Read ↗

The RNA-binding protein FCA and the adaptor protein ECAP coordinately repress FLC to facilitate flowering in Arabidopsis.Semantic proximity Read ↗

Altered interactions within FY/AtCPSF complexes required for Arabidopsis FCA-mediated chromatin silencing.Semantic proximity Read ↗

An allelic series reveals essential roles for FY in plant development in addition to flowering-time control.Semantic proximity Read ↗

The Arabidopsis RNA-binding protein FCA requires a lysine-specific demethylase 1 homolog to downregulate FLC.Semantic proximity Read ↗

The spen family protein FPA controls alternative cleavage and polyadenylation of RNA.Semantic proximity Read ↗

FY is an RNA 3' end-processing factor that interacts with FCA to control the Arabidopsis floral transition.Semantic proximity Read ↗

Functional redundancy and new roles for genes of the autonomous floral-promotion pathway.Semantic proximity Read ↗

Regulation of flowering time by the protein arginine methyltransferase AtPRMT10.Semantic proximity Read ↗

The late flowering phenotype of fwa mutants is caused by gain-of-function epigenetic alleles of a homeodomain gene.Semantic proximity Read ↗

The P-body component DECAPPING5 and the floral repressor SISTER OF FCA regulate FLOWERING LOCUS C transcription in Arabidopsis.Semantic proximity Read ↗

Inverted-Repeat RNAs Targeting FT Intronic Regions Promote FT Expression in Arabidopsis.Semantic proximity Read ↗

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