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Article

Low TNF-induced NF-kappaB and p38 phosphorylation levels in leucocytes in tumour necrosis factor receptor-associated periodic syndrome.

Rheumatology (Oxford, England) - 1 Feb 2010

Stjernberg-Salmela Susanna, Ranki Annamari, Karenko Leena, Siitonen Sanna, Mustonen Harri, Puolakkainen Pauli, Sarna Seppo, Pettersson Tom, Repo Heikki

Abstract excerpt

OBJECTIVE: TNF receptor-associated periodic syndrome (TRAPS) is a systemic autoinflammatory disorder caused by mutations in the type 1 TNF receptor (TNFRSF1A) gene. Because the pathomechanism of TRAPS may involve aberrant TNF-mediated intracellular signalling, we examined phosphorylation levels o...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Familial Mediterranean Fever

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Share to Receptors, Tumor Necrosis Factor, Type I

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Source

Identifiers

PMID: 20071450
DOI: 10.1093/rheumatology/kep327

Genes

TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20071450-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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