Article
Exploring phenotype-associated modules in an oral cavity tumor using an integrated framework.
Bioinformatics (Oxford, England) - 15 Mar 2009
Sun Zhirong, Luo Jie, Zhou Yun, Luo Junjie, Liu Ke, Li Wenting
Abstract excerpt
MOTIVATION: Like most human diseases, tumors are complex traits, the genesis and development of which recruit a number of genes and several important biological processes. As proteins involved in common processes tend to be centralized in the same local area of protein-protein interaction networks, here a novel framework has been developed to identify which areas of the networks are most relevant to a phenotype....
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