Article
FUS/TLS genetic variability in sporadic frontotemporal lobar degeneration.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Cantoni Claudia, Fenoglio Chiara, Cortini Francesca, Venturelli Eliana, Villa Chiara, Clerici Francesca, Marcone Alessandra, Benussi Luisa, Ghidoni Roberta, Gallone Salvatore, Scalabrini Diego, Franceschi Massimo, Cappa Stefano, Binetti Giuliano, Mariani Claudio, Rainero Innocenzo, Giordana Maria Teresa, Bresolin Nereo, Scarpini Elio, Galimberti Daniela
Abstract excerpt
Two hundred and fifty one Italian patients with sporadic frontotemporal lobar degeneration (FTLD) and 259 age-matched controls were tested for association with the tagging single nucleotide polymorphisms (SNPs) rs741810 and rs1052352 in the fused in sarcoma/translated in liposarcoma gene (FUS/TLS). Only patients negative for GRN mutations were included. Considering each SNP alone, no differences in either allelic...
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