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Article

Tricarboxylic acid cycle-dependent synthesis of Staphylococcus aureus Type 5 and 8 capsular polysaccharides.

Journal of bacteriology - 1 Mar 2010

Sadykov Marat R, Mattes Theodoric A, Luong Thanh T, Zhu Yefei, Day Shandra R, Sifri Costi D, Lee Chia Y, Somerville Greg A

Abstract excerpt

Staphylococcus aureus capsule synthesis requires the precursor N-acetyl-glucosamine; however, capsule is synthesized during post-exponential growth when the availability of N-acetyl-glucosamine is limited. Capsule biosynthesis also requires aerobic respiration, leading us to hypothesize that capsule synthesis requires tricarboxylic acid cycle intermediates. Consistent with this hypothesis, S. aureus tricarboxylic...

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Identifiers

PMID: 20061474
DOI: 10.1128/JB.01377-09
PMCID: PMC2820852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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