Article
Assessing risk factors: prevention of inhibitors in haemophilia.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Mar 2010
Chambost H
Abstract excerpt
The formation of antibodies against factor VIII or factor IX that inhibit replacement therapy is currently the most serious treatment-related complication faced by patients with haemophilia. This review highlights non-modifiable and modifiable risk factors that determine the development of these antibodies. The non-modifiable risk factors include patient genotype for haemophilia, immunogenotype, ethnicity and...
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