Article
Transforming growth factor-beta 1 gene polymorphisms in Korean patients with pre-eclampsia.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Apr 2010
Kim Shin Young, Lim Ji Hyae, Park So Yeon, Yang Jae Hyug, Kim Moon Young, Kim Min Hyoung, Ryu Hyun Mee
Abstract excerpt
PROBLEM: The aim of this study was to investigate whether c.869T>C (Leu10Pro) and c.915G>C (Arg25Pro) polymorphisms in exon1 of the transforming growth factor-beta1 (TGF-beta1) gene are associated with development of pre-eclampsia (PE) in Korean women. METHOD OF STUDY: We analyzed blood samples from 164 patients with PE and 182 healthy pregnant women using the polymerase chain reaction and DNA sequencing....
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