Article
Interferon-gamma gene and interferon-gamma receptor-1 gene polymorphisms in children with tuberculosis from Turkey.
Scandinavian journal of infectious diseases - 1 Jan 2010
Onay Huseyin, Ekmekci Aslihan Yilmaz, Durmaz Burak, Sayin Eren, Cosar Hese, Bayram Nuri, Can Demet, Akin Haluk, Ozkinay Cihangir, Ozkinay Ferda
Abstract excerpt
Macrophage activation by interferon-gamma (IFN-gamma) is important in host resistance to tuberculosis (TB). In this study, the relationships of the +874 T/A polymorphism in the first intron of the IFN-gamma gene and intronic (CA)n polymorphic microsatellite marker of the interferon-gamma receptor 1 (IFN-gammaR1) gene to TB susceptibility were investigated in children. Forty children with TB and 67 age-matched...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
