Article
Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype.
Obesity facts - 1 Jan 2008
Kring Sofia Inez Iqbal, Larsen Lesli Hingstrup, Holst Claus, Toubro Søren, Hansen Torben, Astrup Arne, Pedersen Oluf, Sørensen Thorkild I A
Abstract excerpt
OBJECTIVE: In previous studies of associations of variants in the genes UCP2, UCP3, PPARG2, CART, GRL, MC4R, MKKS, SHP, GHRL, and MCHR1 with obesity, we have used a case-control approach with cases defined by a threshold for BMI. In the present study, we assess the association of seven abdominal, peripheral, and overall obesity phenotypes, which were analyzed quantitatively, and thirteen candidate gene...
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