A missing paradigm: deciphering endocrine innovations among diverging regulations of alleles, paralogous genes and orthologous genes.

Abstract excerpt

In endocrinology, there are many similarities in the regulation of gene expression between alleles, paralogous genes or orthologous genes, at the genetic or epigenetic level. However, there are also major differences in the spatial and temporal expression patterns of these genes, in particular between species. In few cases, it has been shown in vitro and/or in vivo that regulatory differences are mainly due to...

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