Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments

12 Nov 2008

Abstract excerpt

In adult tissues, multi-potent progenitor cells are some of the most primitive members of the developmental hierarchies that maintain homeostasis. That progenitors and their more mature progeny share identical genomes, suggests that fate decisions are directed by interactions with extrinsic soluble factors, ECM, and other cells, as well as physical properties of the ECM. To understand regulation of fate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to Cancer Cells and Metastasis
Share to Developmental Biology and Gene Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20023793
DOI: 10.1039/b816472j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironmentsPMID 20023793Read ↗

Patient-derived scaffolds uncover breast cancer promoting properties of the microenvironmentSemantic proximity Read ↗

Three-dimensional culture of human breast epithelial cells: the how and the why.Semantic proximity Read ↗

Extracellular matrix context shapes morphogenesis and lactation-associated states in human milk-derived mammary organoidsSemantic proximity Read ↗

Myoepithelial molecular markers in human breast carcinoma PMC42-LA cells are induced by extracellular matrix and stromal cells.Semantic proximity Read ↗

Structural Cues from the Tissue Microenvironment Are Essential Determinants of the Human Mammary Epithelial Cell PhenotypeSemantic proximity Read ↗

Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast.Semantic proximity Read ↗

Myoepithelial mRNA expression profiling reveals a common tumor-suppressor phenotype.Semantic proximity Read ↗

Gene expression analysis of in vitro cocultures to study interactions between breast epithelium and stroma.Semantic proximity Read ↗

Age-related gene expression in luminal epithelial cells is driven by a microenvironment made from myoepithelial cells.Semantic proximity Read ↗

Interlobular and intralobular mammary stroma: genotype may not reflect phenotype.Semantic proximity Read ↗

Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cellsSemantic proximity Read ↗

Gap junction communication regulates luminal-myoepithelial crosstalk and cell differentiation in a bilayered human mammary epithelial cell modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.