Article
Natural killer cell activation in the lung allograft early posttransplantation.
Transplantation - 27 Mar 2010
Meehan Aislin C, Sullivan Lucy C, Mifsud Nicole A, Brooks Andrew G, Snell Greg I, Kotsimbos Tom C, Westall Glen P
Abstract excerpt
BACKGROUND: In addition to their known antiviral and host defense functions, emerging evidence suggests that natural killer (NK) cells may influence allograft outcomes after solid organ transplantation. Although it is accepted that NK cells are activated in the absence of self-major histocompatibility complex (MHC) class I molecules, little is known of how NK cell dynamics change after transplantation of a MHC...
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