Exertional Rhabdomyolysis and Malignant Hyperthermia in a Patient with Ryanodine Receptor Type 1 Gene, L-type Calcium Channel α-1 Subunit Gene, and Calsequestrin-1 Gene Polymorphisms

Abstract excerpt

THE relationship between hypermetabolic exertional stress injuries and malignant hyperthermia (MH) has been a topic of debate for almost 30 yr. Central to this debate is the idea that some MH susceptible (MHS) patients may develop awake nonanesthesia-related manifestations similar to that seen in porcine stress syndrome.1–7Although a link has never been established by controlled clinical studies, individual case...

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