Article
Atypical functional properties of GluK3-containing kainate receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Dec 2009
Perrais David, Coussen Françoise, Mulle Christophe
Abstract excerpt
The properties of synaptic receptors determine their mode of action at presynaptic and postsynaptic loci. Here, we investigated the atypical biophysical properties of GluK3-containing kainate receptors, which contribute to presynaptic facilitation at hippocampal mossy fiber synapses. We show, using fast glutamate applications on outside-out patches and kinetic modeling, that the low sensitivity of GluK3 receptors...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
