Article
Identification of the base substitution responsible for the Ag(x/y) polymorphism of apolipoprotein B-100.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 2000
Wu M J, Bütler E, Bütler R, Schumaker V N
Abstract excerpt
The identification of the base substitution responsible for Ag(x/y) completes the description of the antigen group polymorphisms associated with the apolipoprotein B polypeptide. Surprisingly, all five antigen group polymorphisms alter restriction endonuclease cleavage sites and have associated restriction fragment length polymorphisms, thereby providing a convenient alternative for antigen group phenotyping.
Topics
- Apolipoprotein B-100
- Apolipoproteins B
- Base Sequence
- DNA
- Haplotypes
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Genetic