Thyroidal involvement in the expression of avian muscular dystrophy.

doi:10.1016/0024-3205(91)90038-d

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Article

Thyroidal involvement in the expression of avian muscular dystrophy.

Life sciences - 1 Jan 1991

King D B, Entrikin R K

Abstract excerpt

We showed previously that propylthiouracil (PTU), a thyroid inhibitor, could alleviate several major signs of hereditary muscular dystrophy in chickens. The goals of the present investigation were to: (1) determine whether a nearly athyroid condition (achieved within two days after hatching by surgical thyroidectomy plus PTU) during an 11-day period beneficially affects the dystrophic condition when followed by...

Topics

Animals
Body Weight
Chickens
Creatine Kinase
Dose-Response Relationship, Drug
Injections, Subcutaneous
Kinetics
Muscular Dystrophy, Animal
Pectoralis Muscles
Phenotype
Propylthiouracil
Receptors, Thyroid Hormone

Thyroid Gland

Thyroidectomy

Time Factors

Triiodothyronine

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