Article
A shooting algorithm for complex immunodominance control problems.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2009
Zhao Xiaopeng, Yang Ruoting, Zhang Mingjun
Abstract excerpt
Although T cells are able to recognize a wide variety of target peptides, they are often strongly focused on a few of the peptides and leave the rest of them unattended. This phenomenon of strongly biased immune response is known as immunodominance. Mathematically, an immunodominance problem can be formulated using optimal control principles as a two-point boundary-value problem. The solution of this problem is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.