Article
Mean leukocyte telomere length and risk of incident colorectal carcinoma in women: a prospective, nested case-control study.
Clinical chemistry and laboratory medicine - 1 Feb 2010
Lee I-Min, Lin Jennifer, Castonguay Amy J, Barton Nathaniel S, Buring Julie E, Zee Robert Y L
Abstract excerpt
BACKGROUND: To date, no prospective epidemiological data are available, particularly in women, on mean leukocyte telomere length as a risk predictor. METHODS: Using leukocyte DNA samples collected at baseline in a prospective cohort of over 28,000 initially healthy women, we examined the relationship between mean leukocyte telomere repeat copy number to single gene copy number (TSR) in 134 incident cases of...
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