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Article

Inherited GPI deficiency: a disorder of histone hypoacetylation.

Birth defects research. Part C, Embryo today : reviews - 1 Dec 2009

Georgiou Elisabeth, Layton Mark, Karadimitris Anastasios

Abstract excerpt

Co-operative interaction of transcription factors (TF) with epigenetic processes, such as chromatin remodeling and modification (acetylation or methylation), as well as DNA methylation, determine transcriptional activity, activation or repression of a given gene. Mutations disrupting binding of T...

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Share to Sp1 Transcription Factor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19960552
DOI: 10.1002/bdrc.20166

Genes

GPI
PIGM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19960552-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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