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Article

Distribution of CCR5-Delta32, CCR5m303A, CCR2-64I and SDF1-3'A in HIV-1 infected and uninfected high-risk Uighurs in Xinjiang, China.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2010

Tan Xiao-hua, Zhang Jing-yu, Di Chun-hong, Hu Ao-rong, Yang Lei, Qu Shen, Zhao Rong-li, Yang Pei-rong, Guo Shu-xia

Abstract excerpt

BACKGROUND: Genetic variants of the genes encoding HIV-1 co-receptors and their ligands, CCR5-Delta32, CCR5m303A, CCR2-64I and SDF1-3'A, are implicated in the susceptibility to HIV-1 infection, and the prevalence of these mutations varies by ethnicity. However, little is known about their distribution in Uighurs. OBJECTIVES: This study aimed at characterizing the frequency of these HIV-related gene variants in a...

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Source

Identifiers

PMID: 19958843
DOI: 10.1016/j.meegid.2009.11.015

Genes

CCR2
CCR5

Provenance

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