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Short communication: SDF1-3'A gene mutation is correlated with increased susceptibility to HIV type 1 infection by sexual transmission in Han Chinese.

AIDS research and human retroviruses - 1 Nov 2008

Wang Yueyun, Wang Xiaohui, Peng Ji, Chen Lin, Cheng Jinquan, Nie Shaofa, Feng Tiejian, Zhao Guanglu, Zhao Jin, Shi Xiangdong

Abstract excerpt

Limited information is available on host genetic polymorphisms that confer resistance to HIV-1 infection in Han Chinese who persistently remain seronegative (HEPS) despite high exposure to HIV-1 through unprotected sexual activity with known HIV-1-seropositive spouses or long-term sexual partners. The aim of this study was to investigate the correlation of CCR5-Delta32, CCR2b-64I, and SDF1-3'A polymorphisms with...

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Identifiers

PMID: 18928397
DOI: 10.1089/aid.2008.0066

Genes

CCR5

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