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Article

Human Induced Pluripotent Stem Cells on Autologous Feeders

1 Dec 2009

Abstract excerpt

BACKGROUND: For therapeutic usage of induced Pluripotent Stem (iPS) cells, to accomplish xeno-free culture is critical. Previous reports have shown that human embryonic stem (ES) cells can be maintained in feeder-free condition. However, absence of feeder cells can be a hostile environment for pluripotent cells and often results in karyotype abnormalities. Instead of animal feeders, human fibroblasts can be used...

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PMID: 19956543
DOI: 10.1371/journal.pone.0008067

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