Article
Association analyses of the vitamin D receptor gene in 1654 families with type I diabetes.
Genes and immunity - 1 Dec 2009
Kahles H, Morahan G, Todd J A, Badenhoop K
Abstract excerpt
Type I diabetes (T1D) results from interactions between environmental exposures and genetic susceptibility leading to immune dysfunction and destruction of the insulin-producing beta cells of the pancreas. Vitamin D deficiency is likely to be one of the many environmental factors influencing T1D development and diagnosis, and, hence, the hormone receptor gene, VDR, was examined for association with T1D risk. The...
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