Article
Peripheral arterial tonometry in assessing endothelial dysfunction in pediatric sickle cell disease.
Pediatric hematology and oncology - 1 Nov 2009
Sivamurthy Krupa M, Dampier Carlton, MacDermott MaryLou, Maureen Meier, Cahill Michele, Hsu Lewis L
Abstract excerpt
BACKGROUND: SCD is characterized by hemolysis and oxidative stress, resulting in endothelial dysfunction (EDF). Peripheral arterial tonometry (PAT), a noninvasive technology for measuring EDF, utilizes reactive hyperemia following mini-ischemic stress (reactive hyperemia index or RHI). METHODS: The authors studied PAT in 36 SCD children to determine the influence of hemoglobin genotype and treatment on EDF....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.