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Article

Tailoring the definition of the clinical schizophrenia phenotype in linkage studies.

Schizophrenia research - 1 Feb 2010

Krause Verena, Krastoshevsky Olga, Coleman Michael J, Bodkin J Alexander, Lerbinger Jan, Boling Lenore, Johnson Fred, Gibbs Anne, Cole Jonathan O, Huang Zhuying, Mendell Nancy R, Levy Deborah L

Abstract excerpt

The delineation of schizophrenia-related symptomatology is critical to informative clinical phenotyping in linkage studies. A minority of first-degree relatives of schizophrenia and schizoaffective probands (RelSZSA) qualifies for a clinical diagnosis in the schizophrenia spectrum. Schizotypal personality disorder (SPD) is a key component of this spectrum, largely because of its relatively specific familial...

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Identifiers

PMID: 19944571
DOI: 10.1016/j.schres.2009.10.023
PMCID: PMC2818450

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