Article
Diagnostic accuracy and linkage analysis: how useful are schizophrenia spectrum phenotypes?
The American journal of psychiatry - 1 Sept 1995
Faraone S V, Kremen W S, Lyons M J, Pepple J R, Seidman L J, Tsuang M T
Abstract excerpt
OBJECTIVE: Numerous studies suggest that the nonschizophrenic relatives of schizophrenic patients exhibit psychiatric and other features that discriminate them from normal comparison subjects. These features have been put forth as "spectrum" phenotypes that may be variant manifestations of the schizophrenia genotype. However, most of these studies do not address a key measurement question: does the diagnostic...
Topics
- Attention
- Evoked Potentials, Auditory
- Eye Movements
- False Positive Reactions
- Genetic Linkage
- Humans
- Neuropsychological Tests
- Paranoid Personality Disorder
- Phenotype
- Schizophrenia
- Schizophrenic Psychology