Article
[Genotoxicity study of Cortex Fraxini decoction].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica - 1 Sept 2009
Hu Yanping, Song Jie, Wang Xin, Zhang Min, Wang Xiuwen, Li Bo
Abstract excerpt
OBJECTIVE: To investigate the genotoxicity of Cortex Fraxini decoction. METHOD: Mouse lymphoma assay (MLA) and mouse bone marrow micronucleus test (MNT) were used. In MLA, four dose levels of 1.71, 3.42, 6.83 and 13.65 g (crude drug) x L(-1) were exposed with I5178Y cells for 3 hours with and without metabolic activation, then expressed for 2 days. The mutation frequency plates were prepared and incubated for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
