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Article

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins

26 Nov 2009

Abstract excerpt

BACKGROUND: Neuronal ceroid lipofuscinoses (NCLs) comprise at least eight genetically characterized neurodegenerative disorders of childhood. Despite of genetic heterogeneity, the high similarity of clinical symptoms and pathology of different NCL disorders suggest cooperation between different NCL proteins and common mechanisms of pathogenesis. Here, we have studied molecular interactions between NCL proteins,...

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PMID: 19941651
DOI: 10.1186/1471-2121-10-83

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