Article
Evaluation of ABCG2 Expression in Human Embryonic Stem Cells: Crossing the Same River Twice?
18 Nov 2009
Abstract excerpt
A recent publication in Stem Cells states that human embryonic stem (ES) cells do not express ABCG2 and “…absence of ABCG2 is a novel feature of human pluripotent stem cells, which distinguishes them from many other stem cells including mouse ES cells” [1]. This is in sharp contrast to our observations [2] and the report of several other investigators who detected ABCG2 mRNA in various human ES cells [3–6]. The...
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