Article
Arabidopsis SET DOMAIN GROUP2 is required for H3K4 trimethylation and is crucial for both sporophyte and gametophyte development.
The Plant cell - 1 Oct 2010
Berr Alexandre, McCallum Emily J, Ménard Rozenn, Meyer Denise, Fuchs Jörg, Dong Aiwu, Shen Wen-Hui
Abstract excerpt
Histone H3 lysine 4 trimethylation (H3K4me3) is abundant in euchromatin and is in general associated with transcriptional activation in eukaryotes. Although some Arabidopsis thaliana SET DOMAIN GROUP (SDG) genes have been previously shown to be involved in H3K4 methylation, they are unlikely to be responsible for global genome-wide deposition of H3K4me3. Most strikingly, sparse knowledge is currently available...
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