Article
A survey of plasmid-mediated fluoroquinolone resistance genes from Escherichia coli isolates and their dissemination in Shandong, China.
Foodborne pathogens and disease - 1 Feb 2010
Xia Li-Ning, Li Lin, Wu Cong-Ming, Liu Yu-Qing, Tao Xiao-Qi, Dai Lei, Qi Yong-Hua, Lu Li-Ming, Shen Jian-Zhong
Abstract excerpt
Bacterial resistance to fluoroquinolones result from mutations in the quinolone resistance-determining regions of the drug targets, overexpression of efflux pumps, and/or the more recently identified plasmid-mediated low-level resistance mechanisms. We investigated the prevalence of and characterized plasmid-mediated fluoroquinolone resistance genes (qnrA, qnrB, qnrS, aac(6')-Ib-cr, and qepA) by polymerase chain...
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