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Article

Intrarenal Expression of miRNAs in Patients With Hypertensive Nephrosclerosis

12 Nov 2009

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are non-coding, single-stranded RNA molecules that play important roles in a number of physiological and pathological processes. Previous studies showed that miRNAs targeting transcription factors ZEB1 and ZEB2 may repress epithelial-mesenchymal transition (EMT). METHODS: We studied 34 consecutive patients with biopsy-proven hypertensive nephrosclerosis. Intrarenal expression of...

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PMID: 19910931
DOI: 10.1038/ajh.2009.208

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