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Internal Transcribed Spacer Region Sequence Heterogeneity in <i>Rhizopus microsporus</i> : Implications for Molecular Diagnosis in Clinical Microbiology Laboratories

12 Nov 2009

Abstract excerpt

Although internal transcribed spacer region (ITS) sequence heterogeneity has been reported in a few fungal species, it has very rarely been reported in pathogenic fungi and has never been described in Mucorales, causes of the highly fatal mucormycosis. In a recent outbreak investigation of intestinal mucormycosis due to Rhizopus microsporus infection in patients with hematological malignancies, PCR of the ITS of...

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PMID: 19906897
DOI: 10.1128/jcm.01750-09

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