Article
Genetic diversity of clinical and environmental Mucorales isolates obtained from an investigation of mucormycosis cases among solid organ transplant recipients.
Microbial genomics - 1 Dec 2020
Nguyen M Hong, Kaul Drishti, Muto Carlene, Cheng Shaoji J, Richter R Alex, Bruno Vincent M, Liu Guojun, Beyhan Sinem, Sundermann Alexander J, Mounaud Stephanie, Pasculle A William, Nierman William C, Driscoll Eileen, Cumbie Richard, Clancy Cornelius J, Dupont Christopher L
Abstract excerpt
Mucormycoses are invasive infections by Rhizopus species and other Mucorales. Over 10 months, four solid organ transplant (SOT) recipients at our centre developed mucormycosis due to Rhizopus microsporus (n=2), R. arrhizus (n=1) or Lichtheimia corymbifera (n=1), at a median 31.5 days (range: 13-34) post-admission. We performed whole genome sequencing (WGS) on 72 Mucorales isolates (45 R. arrhizus, 19 R. delemar,...
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