Article
The relationship between mutation frequency and replication strategy in positive-sense single-stranded RNA viruses.
Proceedings. Biological sciences - 7 Mar 2010
Thébaud Gaël, Chadoeuf Joël, Morelli Marco J, McCauley John W, Haydon Daniel T
Abstract excerpt
For positive-sense single-stranded RNA virus genomes, there is a trade-off between the mutually exclusive tasks of transcription, translation and encapsidation. The replication strategy that maximizes the intracellular growth rate of the virus requires iterative genome transcription from positive...
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