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Article

Loss of collapsin response mediator Protein1, as detected by iTRAQ analysis, promotes invasion of human gliomas expressing mutant EGFRvIII.

Cancer research - 15 Nov 2009

Mukherjee Joydeep, DeSouza Leroi V, Micallef Johann, Karim Zia, Croul Sid, Siu K W Michael, Guha Abhijit

Abstract excerpt

Glioblastoma multiforme (GBM) is the most common and lethal primary human brain tumor. GBMs are characterized by a variety of genetic alterations, among which oncogenic mutations of epidermal growth factor receptor (EGFRvIII) is most common. GBMs harboring EGFRvIII have increased proliferation an...

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Source

Identifiers

PMID: 19903856
DOI: 10.1158/0008-5472.CAN-09-1778

Genes

CRMP1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19903856-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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