Factors associated with virological response to etravirine in nonnucleoside reverse transcriptase inhibitor-experienced HIV-1-infected patients.

doi:10.1128/AAC.01051-09

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Factors associated with virological response to etravirine in nonnucleoside reverse transcriptase inhibitor-experienced HIV-1-infected patients.

Antimicrobial agents and chemotherapy - 1 Jan 2010

Marcelin Anne-Genevieve, Flandre Philippe, Descamps Diane, Morand-Joubert Laurence, Charpentier Charlotte, Izopet Jacques, Trabaud Mary-Anne, Saoudin Henia, Delaugerre Constance, Tamalet Catherine, Cottalorda Jacqueline, Bouvier-Alias Magali, Bettinger Dominique, Dos Santos Georges, Ruffault Annick, Alloui Chakib, Henquell Cecile, Rogez Sylvie, Barin Francis, Signori-Schmuck Anne, Vallet Sophie, Masquelier Bernard, Calvez Vincent

Abstract excerpt

To identify factors associated with virological response (VR) to an etravirine (ETR)-based regimen, 243 patients previously treated with nonnucleoside reverse transcriptase inhibitors (NNRTIs) were studied. The impact of baseline HIV-1 RNA, CD4 cell count, past NNRTIs used, 57 NNRTI resistance mutations, genotypic sensitivity score (GSS) for nucleoside reverse transcriptase inhibitors (NRTIs) and protease...

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PMID: 19901096
DOI: 10.1128/AAC.01051-09
PMCID: PMC2798499

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