Article
A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitro.
Antimicrobial agents and chemotherapy - 1 Jan 2010
Cheng Yao, Tsou Lun K, Cai Jianfeng, Aya Toshihiro, Dutschman Ginger E, Gullen Elizabeth A, Grill Susan P, Chen Annie Pei-Chun, Lindenbach Brett D, Hamilton Andrew D, Cheng Yung-Chi
Abstract excerpt
Recent years have seen the rapid advancement of new therapeutic agents against hepatitis C virus (HCV) in response to the need for treatment that is unmet by interferon (IFN)-based therapies. Most antiviral drugs discovered to date are small molecules that modulate viral enzyme activities. In the...
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