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Article

Cooperative effect of ribosomal protein s19 and Pim-1 kinase on murine c-Myc expression and myeloid/erythroid cellularity.

Journal of molecular medicine (Berlin, Germany) - 1 Jan 2010

Fröjmark Anne-Sophie, Badhai Jitendra, Klar Joakim, Thuveson Maria, Schuster Jens, Dahl Niklas

Abstract excerpt

Diamond-Blackfan anemia is a bone marrow failure syndrome associated with heterozygous mutations in the ribosomal protein S19 (RPS19) gene in a subgroup of patients. One of the interacting partners with RPS19 is the oncoprotein PIM-1 kinase. We intercrossed Rps19 ( +/- ) and Pim-1 ( -/- ) mice st...

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Source

Identifiers

PMID: 19898770
DOI: 10.1007/s00109-009-0558-9

Genes

RPS19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19898770-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Cooperative effect of ribosomal protein s19 and Pim-1 kinase on murine c-Myc expression and myeloid/erythroid cellularity.PMID 19898770Read ↗

Interactions between RPS19, mutated in Diamond-Blackfan anemia, and the PIM-1 oncoprotein.Semantic proximity Read ↗

Targeted disruption of the ribosomal protein S19 gene is lethal prior to implantation.Semantic proximity Read ↗

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.Semantic proximity Read ↗

Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia.Semantic proximity Read ↗

Ribosomal protein S19 and S24 insufficiency cause distinct cell cycle defects in Diamond-Blackfan anemia.Semantic proximity Read ↗

Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia.Semantic proximity Read ↗

Recent insights into the pathogenesis of Diamond-Blackfan anaemia.Semantic proximity Read ↗

Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.Semantic proximity Read ↗

Ribosomal protein S19 gene mutations in patients with diamond-blackfan anemia and identification of ribosomal protein S19 pseudogenes.Semantic proximity Read ↗

Targeted resequencing and analysis of the Diamond-Blackfan anemia disease locus RPS19.Semantic proximity Read ↗

Ribosomal protein mutations in Korean patients with Diamond-Blackfan anemia.Semantic proximity Read ↗

The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia.Semantic proximity Read ↗

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