Article
Dissecting cross-reactivity in hymenoptera venom allergy by circumvention of alpha-1,3-core fucosylation.
Molecular immunology - 1 Jan 2010
Seismann Henning, Blank Simon, Braren Ingke, Greunke Kerstin, Cifuentes Liliana, Grunwald Thomas, Bredehorst Reinhard, Ollert Markus, Spillner Edzard
Abstract excerpt
Hymenoptera venom allergy is known to cause life-threatening and sometimes fatal IgE-mediated anaphylactic reactions in allergic individuals. About 30-50% of patients with insect venom allergy have IgE antibodies that react with both honeybee and yellow jacket venom. Apart from true double sensitisation, IgE against cross-reactive carbohydrate determinants (CCD) are the most frequent cause of multiple...
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