Article
Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity.
Journal of human genetics - 1 Jan 2008
Kyriakou Theodosios, Collins Laura J, Spencer-Jones Nicola J, Malcolm Claire, Wang Xiaoling, Snieder Harold, Swaminathan Ramasamyiyer, Burling Keith A, Hart Deborah J, Spector Tim D, O'Dell Sandra D
Abstract excerpt
Adiponectin is an insulin sensitiser in muscle and liver, and low serum levels characterise obesity and insulin resistance. Eight tagging single nucleotide polymorphisms (tSNPs) in the ADIPOQ gene and promoter were selected, and association with serum adiponectin was tested, in two independent sa...
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