Article
Epigenetic changes in childhood asthma.
Disease models & mechanisms - 1 Jan 2000
Kumar Rakesh K, Hitchins Megan P, Foster Paul S
Abstract excerpt
Childhood asthma is linked strongly to atopy and is characterised by a T helper 2 (Th2)-polarised immunological response. Epidemiological studies implicate severe lower respiratory tract viral infections, especially in early childhood, and repeated inhalational exposure to allergens as important synergistic factors in the development of asthma. The way in which these and other environmental factors induce stable...
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