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Article

Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia?

3 Nov 2009

Abstract excerpt

BACKGROUND: The hair-follicle bulge has recently been added to a growing list of human tissue compartments that exhibit a complex combination of immunosuppressive mechanisms, termed immune privilege (IP), which seem to restrict immune-mediated injury in specific locations. As epithelial hair-follicle stem cells (eHFSC) reside in the hair-follicle bulge region, it is conceivable that these IP mechanisms protect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19886964
DOI: 10.1111/j.1365-2230.2009.03692.x

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