Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leukemia inhibitory factor gene is associated with schizophrenia and working memory function.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Feb 2010

Okahisa Yuko, Ujike Hiroshi, Kunugi Hiroshi, Ishihara Takeshi, Kodama Masafumi, Takaki Manabu, Kotaka Tatsuya, Kuroda Shigetoshi

Abstract excerpt

Leukemia inhibitory factor (LIF), a member of the interleukin-6 cytokine family, regulates the neuronal phenotype and coordinates astrocyte, oligodendrocyte, microglia, and inflammatory cell responses. The LIF gene is located on 22q12.1-q12.2, a hot spot for schizophrenia. Three polymorphisms of the LIF gene (rs929271, rs737812, and rs929273) were examined in a case-control association study of 390 patients with...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Chi-Square Distribution
Share to Genome-Wide Association Study
Share to Leukemia Inhibitory Factor
Share to Memory, Short-Term
Share to Multivariate Analysis
Share to Neuropsychological Tests
Share to Schizophrenia

Source

Identifiers

PMID: 19879916
DOI: 10.1016/j.pnpbp.2009.10.020

Genes

LIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leukemia inhibitory factor gene is associated with schizophrenia and working memory function.PMID 19879916Read ↗

Association between promoter polymorphisms of the LIFR gene and schizophrenia with persecutory delusion in a Korean population.Semantic proximity Read ↗

Monocytic Subsets and Their Signature Genes Differentially Impact Cortex and Cognition in First-Episode SchizophreniaSemantic proximity Read ↗

Polymorphism in the 3'-UTR of LIF but Not in the ATF6B Gene Associates with Schizophrenia Susceptibility: a Case-Control Study and In Silico Analyses.Semantic proximity Read ↗

Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients.Semantic proximity Read ↗

Meta-Analysis of Cytokine and Chemokine Genes in Schizophrenia.Semantic proximity Read ↗

[Genome-wide association study with memory measures as a quantitative trait locus for schizophrenia].Semantic proximity Read ↗

Working Memory Deficits in Schizophrenia Are Associated With the Rs34884856 Variant and Expression Levels of the NR4A2 Gene in a Sample Mexican Population: A Case Control StudySemantic proximity Read ↗

Polymorphisms in the hypoxia inducible factor binding site of the macrophage migration inhibitory factor gene promoter in schizophrenia.Semantic proximity Read ↗

A genome-wide survey of human short-term memory.Semantic proximity Read ↗

Tumor necrosis factor-alpha -1031T/C polymorphism is associated with cognitive deficits in chronic schizophrenia patients versus healthy controls.Semantic proximity Read ↗

Verbal recall and recognition in twins discordant for schizophrenia.Semantic proximity Read ↗

Neurocognitive disturbances associated with acute infectious mononucleosis, Ross River fever and Q fever: a preliminary investigation of inflammatory and genetic correlates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.