Article
Mannose-binding lectin 2 gene polymorphism in recurrent herpes simplex virus 2 infection.
Human immunology - 1 Apr 2009
Seppänen Mikko, Lokki Marja-Liisa, Lappalainen Maija, Hiltunen-Back Eija, Rovio Anja T, Kares Saara, Hurme Mikko, Aittoniemi Janne
Abstract excerpt
Mannose-binding lectin (MBL) is a complement component and an opsonic factor recognizing and binding to herpes simplex virus 2 (HSV-2). In this study, we assessed the effect of MBL2 genotypes on the risk of recurring HSV-2 infection. The MBL2 structural variant genotype (A/O or O/O) was more common among the patients with recurrent HSV-2 infection compared with healthy controls (47% vs 26%, respectively; odds...
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