Article
[Thyroid carcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jan 1991
Namba H, Izumi M
Abstract excerpt
It is now widely accepted that human neoplasms arise as a result of a sequence of mutations affecting the structure of genes involved in growth control. In humans, indirect measurements based on age dependent tumor incidence predict that, on average, the accumulation of 5 to 6 different steps is needed to initiate tumor formation. These mutations do not appear to be random, in that certain neoplasms show...
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